CD3 anticorps

N° du produit ABIN1177371

Cet anticorps anti-CD3 est un anticorps Souris Monoclonal détectant CD3 dans FACS. Adapté pour Macaque rhésus, Cynomolgus et Babouin. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour CD3 anticorps (ABIN1177371)

Antigène: CD3

Reactivité: Macaque rhésus, Cynomolgus, Babouin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: SP34

Détail du produit anti-CD3 anticorps

Marque: BD Pharmingen™

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Isotype: IgG3 lambda

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2μm sterile filtered.

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Références pour anticorps anti-CD3 (ABIN1177371)

Sancho, Ledbetter, Choi, Kanner, Deans, Terhorst: "CD3-zeta surface expression is required for CD4-p56lck-mediated upregulation of T cell antigen receptor-CD3 signaling in T cells." dans: The Journal of biological chemistry, Vol. 267, Issue 11, pp. 7871-9, (1992) (PubMed).

Détails sur CD3

Antigène: CD3

Autre désignation: CD3

Sujet: Clone SP34 reacts with human form of the 20 kDa epsilon subunit of the CD3 antigen/T-cell receptor (TCR) complex. This clone also cross-reacts with a major subset of peripheral blood lymphocytes, but not monocytes or granulocytes, of rhesus or cynomolgus and pigtail macaque monkeys. The distribution on lymphocytes is similar to that observed with normal human donor lymphocytes, with the majority of CD3-positive cells being negative when dual stained with antibodies to B or NK cell markers.

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway