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ANAPC2 anticorps (C-Term)

ANAPC2 Reactivité: Humain WB, EIA, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN117942
  • Antigène Voir toutes ANAPC2 Anticorps
    ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))
    Épitope
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 810-822, C-Term
    Reactivité
    • 25
    • 12
    • 4
    • 1
    Humain
    Hôte
    • 19
    • 6
    Lapin
    Clonalité
    • 20
    • 4
    Polyclonal
    Conjugué
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ANAPC2 est non-conjugé
    Application
    • 16
    • 11
    • 9
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunoprecipitation (IP)
    Séquence
    Human APC2 (822 aa 93.8 kDa): 1 maaavvvaeg dsdsrpgqel lvawntvstg lvppaalglv ssrtsgavpp keeelraave 61 vlrghglhsv leewfvevlq ndlqanispe fwnaisqcen sadepqclll lldafglles 121 rldpylrsle llekwtrlgl lmgtgaqglr eevhtmlrgv lffstprtfq emiqrlygcf 181 lrvymqskrk geggtdpele geldsryarr ryyrllqspl cagcssdkqq cwcrqaleqf 241 hqlsqvlhrl sllervsaea vtttlhqvtr ermedrcrge yersflrefh kwiervvgwl 301 gkvflqdgpa rpaspeagnt lrrwrchvqr ffyriyaslr ieelfsivrd fpdsrpaied 361 lkyclertdq rqqllvslka aletrllhpg vntcdiitly isaikalrvl dpsmvileva 421 cepirrylrt redtvrqiva gltgdsdgtg dlavelsktd pasletgqds eddsgepedw 481 vpdpvdadpg kssskrrssd iisllvsiyg skdlfineyr slladrllhq fsfspereir 541 nvellklrfg eapmhfcevm lkdmadsrri nanireedek rpaeeqppfg vyavilssef 601 wppfkdekle vpediraale ayckkyeqlk amrtlswkht lglvtmdvel adrtlsvavt 661 pvqavillyf qdqaswtlee lskavkmpva llrrrmsvwl qqgvlreepp gtfsvieeer 721 pqdrdnmvli dsddesdsgm asqadqkeee lllfwtyiqa mltnleslsl driynmlrmf 781 vvtgpalaei dlqelqgylq kkvrdqqlvy sagvyrlpkn cs
    Specificité
    This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This antibody reacts with human APC2. Cross reactivity may also occur with APC2 from other sources. Sufficient sequence differences exist to suggest that this antibody would not react with other RING box proteins such as ROC1 and ROC2.
    Purification
    Delipidation and defibrination.
    Immunogène
    This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 810-822 of Human APC2 (C- terminal) coupled to KLH.
    Top Product
    Discover our top product ANAPC2 Anticorps primaire
  • Indications d'application
    Western blot (1: 500-1: 1,000). Immunoprecipitation: The antibody immunoprecipitates in vitro translated protein andprotein from overexpressing cell lysates (using HeLa and NIH-3T3, and others. Coimmunoprecipitation of related proteins (APC11) does occur. A 93.8 kDa bandcorresponding to human APC2 is detected. Most cell lines or tissues expressing APC2 canbe used as a positive control. ELISA (1: 2,000-1: 10,000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    85 mg/mL (by Refractometry)
    Conseil sur la manipulation
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Wang, Yu, Xiang, Fan, He, Guo, Feng, Deng: "Global transcriptional profiles of Staphylococcus aureus treated with berberine chloride." dans: FEMS microbiology letters, Vol. 279, Issue 2, pp. 217-25, (2008) (PubMed).

  • Antigène
    ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))
    Autre désignation
    APC2 / ANAPC2 (ANAPC2 Produits)
    Synonymes
    anticorps anapc2, anticorps ANAPC2, anticorps DDBDRAFT_0203816, anticorps DDBDRAFT_0234264, anticorps DDB_0203816, anticorps DDB_0234264, anticorps si:ch73-203i15.5, anticorps APC2, anticorps RP11-350O14.5, anticorps 9230107K09Rik, anticorps AL024279, anticorps Apc2, anticorps Emi4, anticorps Imi4, anticorps mKIAA1406, anticorps F28I8.30, anticorps F28I8_30, anticorps anaphase-promoting complex/cyclosome 2, anticorps anaphase promoting complex subunit 2, anticorps anaphase promoting complex subunit 2 L homeolog, anticorps anaphase-promoting complex/cyclosome 2, anticorps Anaphase-promoting complex subunit 2, anticorps ANAPC2, anticorps anapc2.L, anticorps anapc2, anticorps Anapc2, anticorps APC2, anticorps apc-2
    Sujet
    APC2, also known as Anaphase promoting complex subunit 2, APC2, Cyclosome subunit 2, and ANAPC2, is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/cyclosome protein complex promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitors, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains at least eleven subunits. The composition of APC is highly conserved in organisms from yeast to humans. APC2 is a cullin family member that interacts through the cullin domain with ANAPC11 and UBCH10.Synonyms: Anaphase-promoting complex subunit 2, Cyclosome subunit 2, KIAA1406
    ID gène
    29882
    NCBI Accession
    NP_037498
    UniProt
    Q9UJX6
    Pathways
    Regulation of Cell Size
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