CD14 anticorps

N° du produit ABIN118508

L’anticorps Souris Monoclonal anti-CD14 a été validé pour FACS, WB, Func et EIA. Il convient pour détecter CD14 dans des échantillons de Humain, Singe, Porc, Boeuf (Vache), Mouton, Chien, Lapin, Chévre, Cat et Vison.

Aperçu rapide pour CD14 anticorps (ABIN118508)

Antigène: CD14

Reactivité: Humain, Singe, Porc, Boeuf (Vache), Mouton, Chien, Lapin, Chévre, Cat, Vison

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)

Clone: Tük4

Détail du produit anti-CD14 anticorps

Purification: Affinity chromatography on Protein G

niveau d'endotoxine: Low Endotoxin

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry: 1/100 - 1/200, use 10 μL of suggested working dilution to label 1x10^6 cells or 100 μL whole blood. ELISA. Western Blot: under reducing conditions. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

ID gène: 9606

UniProt: P08571

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades