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Integrin beta 2 anticorps (PE)

ITGB2 Reactivité: Humain, Chien FACS Hôte: Rat Monoclonal YFC118-3 PE
N° du produit ABIN118555
  • Antigène Voir toutes Integrin beta 2 (ITGB2) Anticorps
    Integrin beta 2 (ITGB2)
    Reactivité
    • 197
    • 53
    • 45
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Chien
    Hôte
    • 101
    • 97
    • 34
    • 2
    Rat
    Clonalité
    • 136
    • 93
    • 2
    Monoclonal
    Conjugué
    • 96
    • 25
    • 21
    • 19
    • 11
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Integrin beta 2 est conjugé à/à la PE
    Application
    • 129
    • 87
    • 52
    • 52
    • 39
    • 31
    • 29
    • 26
    • 26
    • 26
    • 21
    • 13
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    YFC118.3 was clustered at the Fourth International Workshop on Leucocyte Differentiation Antigen as recognising the CD18 antigen. The main cellular reactivity of antibody YFC 118.3 is a strong reactivity with Leucocytes (platelets negative). YFC118.3 blocks homotypic adhesion and other lymphocyte functions which involve the LFA-1 antigen.
    Purification
    Affinity chromatography on Protein G
    Immunogène
    Human neutrophils. Spleen cells from immunised LOU rats were fused with cells of the Y3/Ag.1.2.3 rat myeloma cell line.
    Clone
    YFC118-3
    Isotype
    IgG2b
    Top Product
    Discover our top product ITGB2 Anticorps primaire
  • Indications d'application
    Flow cytometry: Use 10 μL of neat antibody to label 100 μL whole blood or 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    SM1076R: Restore with 1 mL distilled water. SM1076RT: Restore with 25 μL distilled water.
    Buffer
    PBS, pH 7.2 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot and store antibody and control at -20 °C.
  • Antigène
    Integrin beta 2 (ITGB2)
    Autre désignation
    CD18 / ITGB2 (ITGB2 Produits)
    Synonymes
    anticorps CD18, anticorps LAD, anticorps LCAMB, anticorps LFA-1, anticorps MAC-1, anticorps MF17, anticorps MFI7, anticorps 2E6, anticorps AI528527, anticorps Cd18, anticorps Lfa1, anticorps ITGB2, anticorps itgb2, anticorps itgb2-a, anticorps itgb2-b, anticorps integrin subunit beta 2, anticorps integrin beta 2, anticorps integrin subunit beta 2 S homeolog, anticorps ITGB2, anticorps Itgb2, anticorps itgb2.S
    Sujet
    The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight - known as the b chain, of the LFA-1 complex. The CD18 antigen is non-covalently linked to CD11a, b, c molecules. The CD18 Molecule is the receptor for ICAM-1 and is thus important for cell adhesion.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
    ID gène
    3689
    NCBI Accession
    NP_000202
    UniProt
    P05107
    Pathways
    Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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