ITGA2 anticorps (PE)

N° du produit ABIN118701

Cet anticorps anti-ITGA2 Monoclonal Souris conjugué à PE (Clone AK7) (ABIN118701) détecte spécifiquement ITGA2 dans FACS. L’anticorps est réactif avec des échantillons de Humain et Singe.

Aperçu rapide pour ITGA2 anticorps (PE) (ABIN118701)

Antigène: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: AK7

Détail du produit anti-ITGA2 anticorps (PE)

Specificité: Recognizes the Integrin alpha 2 subunit (CD49b), which is a 160 kDa glycoprotein that non-covalently associates with the 130 kDa integrin beta1 subunit to form the VLA-2 complex.

Purification: Affinity Chromatography on Protein G

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: Use 10 μL of neat antibody to label 10^6 cells or 100 μL human whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1.0 mL distilled water.

Buffer: PBS, pH 7.2 with 0.09 % Sodium Azide as preservative, 1 % BSA and 5 % Sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Détails sur ITGA2

Antigène: ITGA2 (Integrin alpha 2 (ITGA2))

Autre désignation: CD49b / ITGA2

Sujet: Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. CD49b is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta 1 subunit to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, approximately 50 % of monocytes and most adherent cell lines.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2

ID gène: 3673

NCBI Accession: NP_002194

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex