ITGA6 anticorps (FITC)

N° du produit ABIN118733

Détail du produit anti-ITGA6 anticorps (FITC)

Antigène: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA6 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Specificité: This antibody recognises the human VLA-6 cell surface antigen, also known as the a6 Integrin and as CD49f. CD49f is expressed by platelets, weakly by monocytes and by a subset of lymphocytes.

Purification: Affinity chromatography on Protein G.

Immunogène: alpha 6 beta 4 Integrin purified from A431 cells

Clone: 450-30A

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ITGA6

Antigène: ITGA6 (Integrin, alpha 6 (ITGA6))

Autre désignation: CD49f / ITGA6 (ITGA6 Produits)

Synonymes: anticorps CD49f, anticorps ITGA6B, anticorps VLA-6, anticorps 5033401O05Rik, anticorps AI115430, anticorps Cd49f, anticorps ITGA6, anticorps inta6, anticorps im:6897425, anticorps itga6, anticorps si:dkey-32o22.1, anticorps wu:fb80g02, anticorps LOC100221694, anticorps si:dkey-18j14.1, anticorps wu:fl20e08, anticorps zgc:113088, anticorps integrin subunit alpha 6, anticorps integrin alpha 6, anticorps integrin subunit alpha 6 L homeolog, anticorps integrin, alpha 6a, anticorps integrin, alpha 6b, anticorps ITGA6, anticorps Itga6, anticorps itga6.L, anticorps itga6a, anticorps itga6b

Sujet: Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around twenty two different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. Integrin alpha 6 complexes are receptors for laminins, which are components of basement membranes. Integrin alpha 6 complexes may play an important role in embryogenesis.Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6

ID gène: 3655

NCBI Accession: NP_000201

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex