ErbB2/Her2 anticorps

N° du produit ABIN119013

Cet anticorps anti-ErbB2/Her2 Monoclonal Rat (Clone ICR55) (ABIN119013) détecte spécifiquement ErbB2/Her2 dans WB, FACS, IHC (p), IP et IHC (fro). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ErbB2/Her2 anticorps (ABIN119013)

Antigène: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp ErbB2/Her2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: ICR55

Détail du produit anti-ErbB2/Her2 anticorps

Specificité: This antibody recognizes the CD340. ICR55 recognizes epitope E of CD340.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein G

Isotype: IgG2a

Information d'application

Indications d'application: Immunohistochemistry on Frozen and Paraffin Sections. Western Blot. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ErbB2/Her2

Antigène: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Autre désignation: CD340 / ERBB2 / HER2

Sujet: CD340 (c-erbB-2 proto-oncogene), also known as Her2/neu and c-erb B-2 is expressed at the cell surface of a range of tumour cells. In many types of tumour c-erbB-2 expression is related to poor prognosis, with an increased risk of metastasis.Synonyms: HER-2, MNL19, NEU, NEU proto-oncogene, NGL, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, c-erbB-2, p185erbB2

ID gène: 2064

NCBI Accession: NP_001005862

UniProt: P04626

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development