CD80 anticorps (FITC)

N° du produit ABIN119433

Cet anticorps anti-CD80 est un anticorps Souris Monoclonal détectant CD80 dans FACS. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour CD80 anticorps (FITC) (ABIN119433)

Antigène: CD80

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD80 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: MEM-233

Détail du produit anti-CD80 anticorps (FITC)

Specificité: The antibody reacts with CD80.

Immunogène: CD80 fusion protein

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free BSA as a stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Références pour anticorps anti-CD80 (FITC) (ABIN119433)

Ryu, Lee, Hong, Shin, Lim, Park, Shim, Nam, Choi, Kim, Han: "Activation of fractalkine/CX3CR1 by vascular endothelial cells induces angiogenesis through VEGF-A/KDR and reverses hindlimb ischaemia." dans: Cardiovascular research, Vol. 78, Issue 2, pp. 333-40, (2008) (PubMed).

Détails sur CD80

Antigène: CD80

Autre désignation: CD80

Sujet: CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 Molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet, there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80

ID gène: 941

NCBI Accession: NP_005182

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints