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CD59 anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement CD59 dans FACS et Func. Il présente une réactivité envers Humain et Porc.
N° du produit ABIN120694

Aperçu rapide pour CD59 anticorps (ABIN120694)

Antigène

Voir toutes CD59 Anticorps
CD59

Reactivité

  • 160
  • 15
  • 11
  • 8
  • 5
  • 4
  • 3
  • 1
  • 1
Humain, Porc

Hôte

  • 93
  • 90
  • 7
  • 6
Souris

Clonalité

  • 112
  • 81
  • 1
Monoclonal

Conjugué

  • 86
  • 25
  • 15
  • 14
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CD59 est non-conjugé

Application

  • 106
  • 82
  • 67
  • 46
  • 38
  • 30
  • 27
  • 23
  • 16
  • 14
  • 13
  • 13
  • 11
  • 11
  • 9
  • 8
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Functional Studies (Func)

Clone

MEM-129
  • Specificité

    The antibody MEM-129 reacts with CD59 (Protectin).

    Purification

    Thiophilic Adsorption-Affinity Chromatography and Size-Exclusion Chromatography.

    Pureté

    > 95 % (by SDS-PAGE).

    Immunogène

    Human peripheral blood lymphocytes

    Isotype

    IgM
  • Indications d'application

    Flow Cytometry. Functional Studies (The antibody activates T-cells).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4

    Agent conservateur

    Azide free

    Stock

    4 °C

    Stockage commentaire

    Store the antibody undiluted at 4-8 °C. DO NOT FREEZE! Should this product contain a precipitate we recommend microcentrifugation before use.
    Shelf Life: one year from despatch.

    Date de péremption

    12 months
  • Antigène

    CD59

    Autre désignation

    CD59

    Sujet

    CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin

    ID gène

    966

    UniProt

    P13987

    Pathways

    Système du Complément
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