PPM1A anticorps
Aperçu rapide pour PPM1A anticorps (ABIN121149)
Antigène
Voir toutes PPM1A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody detects Protein Phosphatase 2C alpha (PP2C alpha).
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Purification
- Protein-G affinity chromatography
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Immunogène
- Recombinant human PP2C alpha protein
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Isotype
- IgG2b
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Indications d'application
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ELISA. Western blot: Recommended dilution range: 1:250 approx. 1:1000. Recommended starting dilution: 1:250. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.09 % Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody at 2-8 °C for one month or at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
Date de péremption
- 12 months
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- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
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Autre désignation
- Protein Phosphatase 1A / PPM1A
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Sujet
- Protein phosphatase 2C(PP2Cα) is a Mn2+- or Mg2+-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNK MAPK pathways and regulates cellular stress response in eukaryotes. The PPM (metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2C, the prototypical member of the PPM family.Synonyms: PP2C-alpha, PPPM1A, Protein phosphatase 2C isoform alpha, Protein phosphatase IA
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UniProt
- P35813
Antigène
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