Growth Hormone 1 anticorps

N° du produit ABIN121163

L’anticorps Souris Monoclonal anti-Growth Hormone 1 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter Growth Hormone 1 dans des échantillons de Humain.

Aperçu rapide pour Growth Hormone 1 anticorps (ABIN121163)

Antigène: Growth Hormone 1 (GH1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Growth Hormone 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: G3H5

Détail du produit anti-Growth Hormone 1 anticorps

Specificité: The antibody recognizes human Growth Hormone (hGH). Other species not tested.

Purification: Protein-G affinity chromatography

Immunogène: Recombinant human Growth Hormone protein

Isotype: IgG2b

Information d'application

Indications d'application: ELISA. Western blot (1:500 - 1:1,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur Growth Hormone 1

Antigène: Growth Hormone 1 (GH1)

Autre désignation: Somatotropin / Growth Hormone / GH1

Sujet: Human growth hormone(hGH, somatotropin), a protein hormone from the anterior lobe of the pituitary gland, comprises a single polypeptide chain of 191 amino acid residues. The 20KDa variant form of human growth hormone (20KDa hGH) presents in extracts from pituitary glands and it differs from the major form of hGH (22KDa, 191 amino acid) by the deletion of amino acid residues 32-46. The growth hormone amino acid sequence varies considerably between species, and non-primate growth hormones have little activity in man. Main functions of hGH and 20KDa hGH are the stimulation of somatic and bone growth, as well as an increase in the size and mass of organs and tissues. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.Synonyms: Growth hormone 1, HGH, Pituitary growth hormone

ID gène: 2688

UniProt: P01241

Pathways: Signalisation NF-kappaB, Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process