HTR1F anticorps (C-Term)

N° du produit ABIN121983

Cet anticorps anti-HTR1F Polyclonal Lapin (ABIN121983) détecte spécifiquement HTR1F dans IHC (p). L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour HTR1F anticorps (C-Term) (ABIN121983)

Antigène: HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTR1F est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HTR1F anticorps

Épitope: C-Term

Specificité: This antibody detects human Serotonin receptor 1F (HTR1F) at C-term. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HTR1E (71 %), HTR1D (59 %), HTR1B (59 %).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat (see 'Immunogen Remarks')Species reactivity (tested):Human

Purification: Immunoaffinity chromatography

Immunogène: Synthetic peptide - KLH conjugated

Information d'application

Indications d'application: Immunohistochemstry on paraffin embedded sections: 2-3 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur HTR1F

Antigène: HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

Autre désignation: Serotonin Receptor 1F (HTR1F)

Sujet: 5-HT1F, a Serotonin Receptor, is negatively coupled to adenylate cyclase. Selective 5-HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors. Expression of the 5-HT1F receptor has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.Synonyms: 5-HT-1F, 5-hydroxytryptamine receptor 1F, HTR1EL

ID gène: 3355

UniProt: P30939

Pathways: Signalistation JAK/STAT