GPR3 anticorps

N° du produit ABIN122137

Détail du produit anti-GPR3 anticorps

Antigène: GPR3 (G Protein-Coupled Receptor 3 (GPR3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Reacts with G Protein-Coupled Receptor GPR3 (family: GPCR, subfamily: Lysophospholipid/Lysosphingolipid)

Purification: Peptide immunogen affinity column

Immunogène: Synthetic peptide - KLH conjugated

Information d'application

Indications d'application: Immunohistochemistry with formalin fixed paraffin embedded tissues: 6 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur GPR3

Antigène: GPR3 (G Protein-Coupled Receptor 3 (GPR3))

Autre désignation: GPR3 / ACCA (GPR3 Produits)

Synonymes: anticorps GPR3, anticorps ACCA, anticorps Gpcr3, anticorps Gpcr20, anticorps Gpcr21, anticorps G protein-coupled receptor 3, anticorps G-protein coupled receptor 3, anticorps GPR3, anticorps Gpr3

Sujet: GPR3 has been identified as a constitutively active lysophospholipid/lysosphingolipid receptor. GPR3 receptor is a link in communication between the somatic cells and oocyte of the ovarian follicle where GPR3 maintains meiotic arrest in mouse oocytes. Oocytes from Gpr3 knockout mice resume meiosis within antral follicles, independently of an increase in luteinizing hormone, and this phenotype Mice deficient in GPR3 exhibit premature ovarian failure due to early oocyte aging. GPR3 has been reported at low abundance predominantly in the central nervous system and in the lung and kidney. ESTs have been isolated from brain and colon libraries.Synonyms: ACCA orphan receptor, G-protein coupled receptor 3

ID gène: 2827

UniProt: P46089

Pathways: cAMP Metabolic Process