PAK6 anticorps (Linker Domain)

N° du produit ABIN122606

L’anticorps anti-PAK6 Polyclonal Lapin est utilisé pour la détection de PAK6 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour PAK6 anticorps (Linker Domain) (ABIN122606)

Antigène: PAK6 (P21-Activated Kinase 6 (PAK6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK6 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PAK6 anticorps

Épitope: Linker Domain

Specificité: Reacts with P21-Activated Kinase 6 (PAK6) (family: Protein Kinase, subfamily: PAK (STE20))

Attributs du produit: Synonyms: p21-activated kinase 6, PAK-6, Serine/threonine-protein kinase PAK 6, PAK5, PAK-5

Purification: Peptide immunogen affinity column

Immunogène: Synthetic peptide - KLH conjugatedEpitope: Linker domain of humanGenename: PAK6

Information d'application

Indications d'application: Immunohistochemistry on paraffin embedded sections: 3,5 μg/mLAntigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PAK6

Antigène: PAK6 (P21-Activated Kinase 6 (PAK6))

Autre désignation: PAK6

Sujet: PAK6, a PAK (STE20) type protein kinase, contains a N-terminal Cdc42/Rac interactive binding (CRIB) motif and a C-terminal kinase domain. The protein has been shown to bind to GTP-Cdc42 and GTP-Rac, however, in contrast to most PAKs, kinase activity was not stimulated by Cdc42 or Rac, but could be stimulated by androgen receptor (AR) binding. PAK6 protein also has been shown to bind to estrogen receptor alpha. PAK6 also has been called P21-Activated Kinase 5 (PAK5), however, PAK5 is a distinct gene found on chromosome 20 p12.2. PAK6 expression has been documented in normal human brain, breast, prostate and testis. ESTs have been isolated from several tissue libraries, including normal brain and testis and cancerous cervix and smooth muscle.Synonyms: PAK-5, PAK-6, PAK5, Serine/threonine-protein kinase PAK 6, p21-activated kinase 6

ID gène: 56924

UniProt: Q9NQU5