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MAPK7 anticorps (N-Term)

L’anticorps Souris Monoclonal anti-MAPK7 a été validé pour WB. Il convient pour détecter MAPK7 dans des échantillons de Humain, Souris, Rat et Chien.
N° du produit ABIN126797

Aperçu rapide pour MAPK7 anticorps (N-Term) (ABIN126797)

Antigène

Voir toutes MAPK7 Anticorps
MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Reactivité

  • 94
  • 63
  • 58
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Humain, Souris, Rat, Chien

Hôte

  • 124
  • 3
  • 2
  • 1
Souris

Clonalité

  • 116
  • 14
Monoclonal

Conjugué

  • 43
  • 10
  • 7
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
Cet anticorp MAPK7 est non-conjugé

Application

  • 70
  • 54
  • 53
  • 37
  • 23
  • 21
  • 18
  • 13
  • 11
  • 7
  • 5
  • 1
  • 1
Western Blotting (WB)

Clone

12F2
  • Épitope

    • 16
    • 16
    • 15
    • 15
    • 15
    • 15
    • 10
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificité

    This antibody recognizes MAP kinase 7 (erk5) at 92 kDa in Western-blot applications.

    Attributs du produit

    Synonyms: Mitogen-activated protein kinase 7, Extracellular signal-regulated kinase 5, ERK4, Big MAPkinase 1, MAPK7

    Purification

    Size Exclusion Chromatography

    Ingrédients

    incl. positive Control

    Immunogène

    Peptide conjugated to hemocyanin. AA Sequence: N-Terminus

    Isotype

    IgG1
  • Indications d'application

    Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive control: Cell lysate from untreated SKOV-3 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Reconstitution

    Restore with 1 mL H2O (15 min, RT).

    Buffer

    1 mLPBS containing 0.09 % Sodium Azide, PEG and Sucrose

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C/-80 °C

    Stockage commentaire

    Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
    Shelf life: one year from despatch.

    Date de péremption

    12 months
  • Antigène

    MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

    Autre désignation

    MAPK7 / ERK5

    Sujet

    Erk5 (also known as MAPK7 or big mitogen activated kinase 1, BMK1) belongs to the Ser/Thr protein kinase family. It contains a T E Y motif in the activation loop similar to Erk1/2. Extracellular signals, including receptor tyrosine kinases and G-protein-coupled receptors as well as osmotic and oxdative stress lead to Erk5 activation by MEK5. The Erk5 pathway plays an important role in cellular proliferation, differentiation and survival.Synonyms: Big MAP kinase 1, ERK4, Extracellular signal-regulated kinase 5, MAPK7, Mitogen-activated protein kinase 7

    ID gène

    5598

    UniProt

    Q13164

    Pathways

    Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
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