MAPK7 anticorps (N-Term)

N° du produit ABIN126797

L’anticorps anti-MAPK7 Monoclonal Souris est utilisé pour la détection de MAPK7 dans des échantillons de Humain, Souris, Rat et Chien. Il a été validé pour WB.

Aperçu rapide pour MAPK7 anticorps (N-Term) (ABIN126797)

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAPK7 est non-conjugé

Application: Western Blotting (WB)

Clone: 12F2

Détail du produit anti-MAPK7 anticorps

Épitope: N-Term

Specificité: This antibody recognizes MAP kinase 7 (erk5) at 92 kDa in Western-blot applications.

Attributs du produit: Synonyms: Mitogen-activated protein kinase 7, Extracellular signal-regulated kinase 5, ERK4, Big MAPkinase 1, MAPK7

Purification: Size Exclusion Chromatography

Ingrédients: incl. positive Control

Immunogène: Peptide conjugated to hemocyanin. AA Sequence: N-Terminus

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive control: Cell lysate from untreated SKOV-3 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1 mL H2O (15 min, RT).

Buffer: 1 mLPBS containing 0.09 % Sodium Azide, PEG and Sucrose

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C/-80 °C

Stockage commentaire: Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur MAPK7

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Autre désignation: MAPK7 / ERK5

Sujet: Erk5 (also known as MAPK7 or big mitogen activated kinase 1, BMK1) belongs to the Ser/Thr protein kinase family. It contains a T E Y motif in the activation loop similar to Erk1/2. Extracellular signals, including receptor tyrosine kinases and G-protein-coupled receptors as well as osmotic and oxdative stress lead to Erk5 activation by MEK5. The Erk5 pathway plays an important role in cellular proliferation, differentiation and survival.Synonyms: Big MAP kinase 1, ERK4, Extracellular signal-regulated kinase 5, MAPK7, Mitogen-activated protein kinase 7

ID gène: 5598

UniProt: Q13164

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling