FADD anticorps

N° du produit ABIN126919

Cet anticorps Souris Monoclonal détecte spécifiquement FADD dans WB. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour FADD anticorps (ABIN126919)

Antigène: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FADD est non-conjugé

Application: Western Blotting (WB)

Clone: T1B

Détail du produit anti-FADD anticorps

Specificité: The antibody detects 28 kDa protein, corresponding to the apparent molecular weight of FADD in SDS-PAGE immunoblots.

Attributs du produit: Synonyms: FAS-associated death domain protein, MORT1, GIG3, FAS-associating deathdomain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3protein

Purification: Affinity chromatography

Immunogène: Recombinant human FADD

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1-4 μg/mL, HeLa cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS containing 30 % glycerol, 0.5 % BSA and 0.01 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C to -70 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur FADD

Antigène: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Autre désignation: FADD

Sujet: Fas-associating death domain containing protein (FADD), also known as mediator of receptor induced toxicity (MORT1), is a 24 kDa cytosolic protein. The protein is involved in both Fas and TNF-R induced cell death pathway. FADD specifically binds to Fas, an association mediated by their homologous death domains. Overexpression of FADD induces apoptosis that can be inhibited by CrmA, a poxvirus protein that blocks both Fas- and TNF-induced cell death.Synonyms: FAS-associated death domain protein, FAS-associating death domain-containing protein, GIG3, Growth-inhibiting gene 3 protein, MORT1, Mediator of receptor induced toxicity

ID gène: 8772

UniProt: Q13158

Pathways: Apoptose, Signalisation TLR, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades