Caspase 3 anticorps (active, Cleavage Site, N-Term)

N° du produit ABIN126957

Cet anticorps anti-Caspase 3 est un anticorps Lapin Polyclonal détectant Caspase 3 dans WB et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Caspase 3 anticorps (active, Cleavage Site, N-Term) (ABIN126957)

Antigène: Caspase 3 (CASP3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Caspase 3 anticorps

Épitope: active, Cleavage Site, N-Term

Specificité: The antibody preferentially recognizes the p17 fragment of the active caspase-3.

Purification: Affinity chromatography

Immunogène: Synthetic peptide mapping to the N-terminus adjacent to the cleavage site of human caspase-3

Information d'application

Indications d'application: Western Blot: 0.5-4 μg/mL. Immunohistochemistry on paraffin sections: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C to -70 °C.

Détails sur Caspase 3

Antigène: Caspase 3 (CASP3)

Autre désignation: Caspase-3

Sujet: Caspase-3 has been extensively studied and implicated to play an important role in apoptosis. Active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP). The affinity purified antibody recognizing the active forms of caspase-3 provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells.Synonyms: Apopain, CASP-3, CASP3, CPP-32, CPP32, Cysteine protease CPP32, SCA-1, SCA1, SREBP cleavage activity 1, Yama protein

ID gène: 836

NCBI Accession: NP_004337

UniProt: P42574

Pathways: Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation