Caspase 4 anticorps

N° du produit ABIN126973

Détail du produit anti-Caspase 4 anticorps

Antigène: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 4 est non-conjugé

Application: Western Blotting (WB)

Specificité: The affinity purified antibody detects the 43 kDa proform of caspase-4.

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide surrounding amino acid 100 of human caspase-4

Information d'application

Indications d'application: Western Blot: 0,5-4g/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur Caspase 4

Antigène: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Autre désignation: Caspase-4 (CASP4 Produits)

Synonymes: anticorps ICE(rel)II, anticorps ICEREL-II, anticorps ICH-2, anticorps Mih1/TX, anticorps TX, anticorps Casp11, anticorps CASP13, anticorps CASP1, anticorps CASP4, anticorps Caspl, anticorps ich-3, anticorps Casp4, anticorps caspase 4, anticorps caspase 4, apoptosis-related cysteine peptidase, anticorps caspase-4, anticorps CASP4, anticorps Casp4, anticorps LOC100731032

Sujet: Apoptosis occurs during normal cellular development and involves dramatic changes in cellular structure. Disruption of apoptosis may contribute to cancer as well as other autoimmune diseases. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-4 is also known as Ich-2, TX, and ICErel-II and can proteolytically processed by granzyme B. Over expression of caspase-4 induces apoptosis in Rat-1 and HeLa cells, which can be inhibited by CrmA and Bcl-2.Synonyms: CASP4, ICE(rel)-II, ICH2, Protease ICH-2, Protease TX

ID gène: 837

NCBI Accession: NP_001216

UniProt: P49662

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity