FADD anticorps
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- Antigène Voir toutes FADD Anticorps
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FADD est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Specificité
- The antibody detects an ~28 kDa band, corresponding to the expected molecular mass of FADD on immunoblots. The antibody specificity is confirmed by specific peptide inhibition in immunoblotting studies.
- Purification
- Affinity chromatography
- Immunogène
- Synthetic peptide surrounding amino acid 128 of human FADD
- Top Product
- Discover our top product FADD Anticorps primaire
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- Indications d'application
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Western Blot: 0.5-4 μg/mL. Based on researcher's feedback, it can also be used in immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.
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- Antigène
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
- Autre désignation
- FADD (FADD Produits)
- Synonymes
- anticorps MORT1, anticorps Mort1/FADD, anticorps Mort1, anticorps TNFRSF6, anticorps adaptor, anticorps fadd, anticorps mort1, anticorps xfadd, anticorps Fas associated via death domain, anticorps Fas (TNFRSF6)-associated via death domain, anticorps Fas associated via death domain S homeolog, anticorps Fas (tnfrsf6)-associated via death domain, anticorps FADD, anticorps Fadd, anticorps fadd.S, anticorps fadd
- Sujet
- Fas-associating death domain containing protein (FADD), also known as mediator of receptor induced toxicity (MORT1), is a 23 kDa cytosolic protein with an apparent molecular weight of 28 kDa on SDS-PAGE. The protein is involved in both Fas and TNF-R induced cell death pathway. FADD specifically binds to Fas to initiate the apoptotic signalling cascade. Overexpression of FADD induces apoptosis.Synonyms: FAS-associated death domain protein, FAS-associating death domain-containing protein, GIG3, Growth-inhibiting gene 3 protein, MORT1, Mediator of receptor induced toxicity
- ID gène
- 8772
- NCBI Accession
- NP_003815
- UniProt
- Q13158
- Pathways
- Apoptose, Signalisation TLR, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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