NAIP anticorps
Aperçu rapide pour NAIP anticorps (ABIN127053)
Antigène
Voir toutes NAIP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects NAIP.
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Purification
- Affinity purified
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Immunogène
- Synthetic peptide surrounding amino acid 506 of human NAIP.
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Indications d'application
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Western Blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C/-80 °C
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Stockage commentaire
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))
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Autre désignation
- NAIP
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Sujet
- NAIP (neuronal apoptosis inhibitor protein) is a member of the IAPs (inhibitor of apoptosis proteins) that function in cell death pathways to inhibit apoptosis. NAIP was discovered based on its association with a neurodegenerative disorder. Mutations and deletions in the NAIP gene locus is a contributing factor in spinal muscular atrophy. Coexpression of NAIP and hippocalcin protects neurons against calcium-induced cell death. NAIP is strongly expressed in anterior horn and motor cortex neurons of the normal brain. It is also found in human fetal neurons and in adult choroid plexus cells.Synonyms: BIRC1, Baculoviral IAP repeat-containing protein 1
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ID gène
- 100510692
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NCBI Accession
- NP_004527
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UniProt
- Q13075
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Pathways
- Apoptose, Inflammasome
Antigène
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