RASA1 anticorps

N° du produit ABIN127081

Cet anticorps Lapin Polyclonal détecte spécifiquement RASA1 dans WB, IHC (p) et IP. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour RASA1 anticorps (ABIN127081)

Antigène: RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Détail du produit anti-RASA1 anticorps

Specificité: The antibody recognizes ~120 kDa Ras GAP

Purification: Protein A purified

Immunogène: Synthetic peptide surrounding amino acid 1025 of human RasGAP

Information d'application

Indications d'application: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL. Jurkat cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur RASA1

Antigène: RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))

Autre désignation: RASA1 / RasGAP

Sujet: The mammalian proto-oncogene Ras encodes 21 kDa proteins (p21Ras) which exists in either a physiologically quiescent GDP-binding state or a GTPbinding signal-emitting state. Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold. The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity.Synonyms: GAP, RASA, Ras GTPase-activating protein 1, Ras p21 protein activator, p120GAP, p120RASGAP

ID gène: 5921

NCBI Accession: NP_002881

UniProt: P20936

Pathways: Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals