RASA1 anticorps (C-Term)

N° du produit ABIN3043368

Détail du produit anti-RASA1 anticorps

Antigène: RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))

Épitope: AA 1018-1047, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASA1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Ras GTPase-activating protein 1(RASA1) detection. Tested with WB in Human.

Séquence: AQQHVLKKLL AITELLQQKQ NQYTKTNDVR

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Ras GTPase-activating protein 1(RASA1) detection. Tested with WB in Human.
Gene Name: RAS p21 protein activator (GTPase activating protein) 1
Protein Name: Ras GTPase-activating protein 1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human RASA1 (1018-1047aa AQQHVLKKLLAITELLQQKQNQYTKTNDVR), different from the related rat sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur RASA1

Antigène: RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))

Autre désignation: RASA1 (RASA1 Produits)

Synonymes: anticorps CG9209, anticorps D-RasGAP, anticorps Dmel\\CG9209, anticorps RAS-GAP, anticorps RasGAP, anticorps RasGap, anticorps rasGap, anticorps CM-AVM, anticorps CMAVM, anticorps GAP, anticorps PKWS, anticorps RASA, anticorps RASGAP, anticorps p120GAP, anticorps p120RASGAP, anticorps GAPX, anticorps Rasa, anticorps Gap, anticorps vacuolar peduncle, anticorps RAS p21 protein activator 1, anticorps vap, anticorps RASA1, anticorps Rasa1

Sujet: RASA1, also known as RAS p21 protein activator 1, is a 120- kDacytosolic human protein. The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.

Synonyms: CM AVM antibody|CMAVM antibody|DKFZp434N071 antibody|GAP antibody|GTPase activating protein antibody|GTPase-activating protein antibody|OTTHUMP00000222390 antibody|OTTHUMP00000222391 antibody|OTTHUMP00000222392 antibody|OTTHUMP00000222393 antibody|p120GAP antibody|p120RASGAP antibody|PKWS antibody|Ras GTPase-activating protein 1 antibody|RAS p21 protein activator (GTPase activating protein) 1 antibody|Ras p21 protein activator antibody|RASA antibody|RASA1 antibody|RASA1_HUMAN antibody|RasGAP antibody| Triphosphatase activating protein antibody

ID gène: 5921

UniProt: P20936

Pathways: Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals