anticorps mapkapk2, anticorps wu:fb30e10, anticorps wu:fc56c10, anticorps wu:fi03a01, anticorps MGC78852, anticorps MAPKAPK2, anticorps AA960234, anticorps MAPKAP-K2, anticorps MK-2, anticorps MK2, anticorps Rps6kc1, anticorps mitogen-activated protein kinase-activated protein kinase 2a, anticorps mitogen-activated protein kinase-activated protein kinase 2 L homeolog, anticorps mitogen-activated protein kinase-activated protein kinase 2, anticorps MAP kinase-activated protein kinase 2, anticorps mapkapk2a, anticorps mapkapk2.L, anticorps MAPKAPK2, anticorps Mapkapk2
Sujet
MAP kinase-activated protein kinase-2 (MAPKAPK-2), also known as p45 hsp27 kinase, is a 45-54 kDa serine-threonine protein kinase. MAPKAPK-2 is rapidly phosphorylated and activated in response to stress, cytokines, and chemotactic factors. One of the major substrates of MAPKAPK-2 is hsp27, which stimulates actin polymerization in order to facilitate recovery from destruction of cytoskeleton during cellular stresses. Two isoforms are produced due to alternative splicing of the same gene which differ in their C-terminals. This antibody recognizes both isoforms.Synonyms: MAP kinase-activated protein kinase 2, MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MAPKAPK2, MK2