MAPKAP Kinase 2 anticorps (Thr334)
Aperçu rapide pour MAPKAP Kinase 2 anticorps (Thr334) (ABIN127115)
Antigène
Voir toutes MAPKAP Kinase 2 (MAPKAPK2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Thr334
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Specificité
- The antibody detects phosphorylated MAPKAPK-2 (Thr334).
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Purification
- Affinity purified
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Immunogène
- Synthetic peptide corresponding to residues surrounding Thr334 of human MAPKAPK-2
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Indications d'application
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Western Blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C/-80 °C
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Stockage commentaire
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
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Autre désignation
- MAPKAP Kinase-2
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Sujet
- MAP kinase-activated protein kinase-2 (MAPKAPK-2), also known as p45 hsp27 kinase, is a 45-54 kDa serine-threonine protein kinase. MAPKAPK-2 is rapidly phosphorylated and activated in response to stress, cytokines, and chemotactic factors. One of the major substrates of MAPKAPK-2 is hsp27, which stimulates actin polymerization in order to facilitate recovery from destruction of cytoskeleton during cellular stresses. Two isoforms are produced due to alternative splicing of the same gene which differ in their C-terminals. This antibody recognizes both isoforms.Synonyms: MAP kinase-activated protein kinase 2, MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MAPKAPK2, MK2
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ID gène
- 9261
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NCBI Accession
- NP_004750
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UniProt
- P49137
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Pathways
- Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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