PAK4 anticorps (N-Term)
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- Antigène Voir toutes PAK4 Anticorps
- PAK4 (P21-Activated Kinase 4 (PAK4))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAK4 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- The antibody recognizes 72 kDa Pak4. It does not cross-react with other Paks.
- Purification
- Antigen affinity purified
- Immunogène
- Synthetic peptide corresponding to the N-terminus of human Pak4
- Top Product
- Discover our top product PAK4 Anticorps primaire
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- Indications d'application
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Western Blot: 1 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C/-80 °C
- Stockage commentaire
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- Antigène
- PAK4 (P21-Activated Kinase 4 (PAK4))
- Autre désignation
- PAK4 (PAK4 Produits)
- Synonymes
- anticorps 5730488L07Rik, anticorps AW555722, anticorps mKIAA1142, anticorps im:5916170, anticorps wu:fd12b01, anticorps zgc:92014, anticorps p21 (RAC1) activated kinase 4, anticorps p21 protein (Cdc42/Rac)-activated kinase 4, anticorps PAK4, anticorps Pak4, anticorps pak4
- Sujet
- The PAK (p21-activated kinase) family of serine/threonine kinases plays an important role in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, etc. Several mechanisms that induce PAK activation have been reported. Binding of Rac/cdc42 to the CRIB (or PBD) domain at the N-terminal region of PAK causes autophosphorylation and conformational change of PAK. More recently identified members PAK4, PAK5 and PAK6 have lower sequence similarity with PAK1-3 in the regulatory N-terminal region. It has been demonstrated that phosphorylation of serine 474 of PAK4 may play a pivotal role in the activity and function of PAK4 kinase.Synonyms: KIAA1142, PAK 4, PAK-4, Serine/threonine-protein kinase PAK 4, p21-activated kinase 4
- ID gène
- 10298
- NCBI Accession
- NP_001014831
- UniProt
- O96013
- Pathways
- Signalisation RTK
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