BRCA2 anticorps (N-Term)

N° du produit ABIN127309

Détail du produit anti-BRCA2 anticorps

Antigène: BRCA2 (Breast Cancer 2, Early Onset (BRCA2))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRCA2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects BRCA2.

Purification: Affinity Chromatography.

Immunogène: Synthetic peptide mapping to the N-terminus of Human BRCA2.

Information d'application

Indications d'application: Western Blot: 0.5-4 μg/mL. HeLa cell lysate can be used as a Positive Control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS pH 7.2, containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur BRCA2

Antigène: BRCA2 (Breast Cancer 2, Early Onset (BRCA2))

Autre désignation: BRCA2 / FANCD1 (BRCA2 Produits)

Synonymes: anticorps BRCC2, anticorps BROVCA2, anticorps FACD, anticorps FAD, anticorps FAD1, anticorps FANCB, anticorps FANCD, anticorps FANCD1, anticorps GLM3, anticorps PNCA2, anticorps 30169, anticorps BcDNA:SD25109, anticorps CG13583, anticorps CG13584, anticorps CG30169, anticorps Dmel\\CG30169, anticorps brca2, anticorps dmbrca2, anticorps fancd1, anticorps BRCA2, anticorps brcc2, anticorps brovca2, anticorps facd, anticorps fad, anticorps fad1, anticorps fancb, anticorps AI256696, anticorps AW045498, anticorps Fancd1, anticorps RAB163, anticorps BRCA2, DNA repair associated, anticorps Breast cancer 2, early onset homolog, anticorps breast cancer 2, early onset, anticorps BRCA2, anticorps Brca2, anticorps brca2, anticorps LOC584780

Sujet: BRCA 1 and 2 are breast cancer susceptibility proteins that plays a role in DNA damage, repair, cell cycle progression, transcription and apoptosis, etc. The BRCA1 gene is expressed in numerous tissues, including breast and ovary, and encodes a predicted protein of 1863 amino acids. BRCA2 has been shown to be required for localization of Rad51 to sites of DSBs (double stranded breaks) in DNA. Cells lacking BRCA1 and BRCA2 cannot repair DSBs through the Rad51-dependent process.Synonyms: Breast cancer type 2 susceptibility protein, FACD, Fanconi anemia group D1 protein

ID gène: 675

NCBI Accession: NP_000050

UniProt: P51587

Pathways: Réparation de l'ADN, M Phase, Maintenance of Protein Location