MMP12 anticorps

N° du produit ABIN127325

Détail du produit anti-MMP12 anticorps

Antigène: MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP12 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody recognizes the MMP-12.

Purification: Affinity Chromatography.

Immunogène: Synthetic peptide surrounding amino acid 460 of Human MMP-12

Information d'application

Indications d'application: Western Blot: 0.5-4.0 μg/mL. Mouse small intestine tissue lysate can be used as a Positive Control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 30 % Glycerol and 0.02 % Thimerosal.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur MMP12

Antigène: MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))

Autre désignation: MMP-12 (MMP12 Produits)

Synonymes: anticorps MMP12, anticorps AV378681, anticorps Mmel, anticorps Mme, anticorps HME, anticorps ME, anticorps MME, anticorps MMP-12, anticorps matrix metallopeptidase 12, anticorps MMP12, anticorps Mmp12

Sujet: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration through the epidermal and vascular basement membranes in inflammatory disorders.Synonyms: HME, ME, MMP12, Macrophage elastase, Macrophage metalloelastase, Matrix metalloproteinase-12

ID gène: 4321

NCBI Accession: NP_002417

UniProt: P39900