FGFR4 anticorps

N° du produit ABIN1302415

Cet anticorps anti-FGFR4 est un anticorps Souris Monoclonal détectant FGFR4 dans FACS et ICC. Adapté pour Humain.

Aperçu rapide pour FGFR4 anticorps (ABIN1302415)

Antigène: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FGFR4 est non-conjugé

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 4FR6D3

Détail du produit anti-FGFR4 anticorps

Fonction: Anti-Hu CD334 Purified

Specificité: The mouse monoclonal antibody 4FR6D3 reacts with an extracellular epitope of CD334, the fibroblast growth factor receptor 4, which is an approximately 88 kDa receptor tyrosine kinase expressed in variety of tissues.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: NIH 3T3 cells transfected with full length human CD334

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 2-6 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur FGFR4

Antigène: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Autre désignation: CD334

Sujet: Fibroblast growth factor receptor 4,CD334 / FGFR4 (fibroblast growth factor receptor 4), a transmembrane tyrosine kinase, which is expressed in many tissues, such as in lung, kidney, muscle, heart, pancreas, intestine and other, acts as a receptor for several fibroblast growth factors, namely FGF1, FGF2, FGF6, FGF8, and FGF19. Interaction with these growth factors initiates in cell the signaling cascades leading to the mitogenesis and cell differentiation. Presence of CD334 Gly338Arg allele correlates with prognostic parameters in various cancer studies. CD334 plays multiple roles in the organism, including those of muscle regeneration, cholesterol-to-bile acid metabolism, or glucose homeostasis.,FGFR4, TKF, JTK2, FGFR-4

ID gène: 2264

UniProt: P22455

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding