Caspase 1 anticorps

N° du produit ABIN1305223

Cet anticorps détecte spécifiquement Caspase 1 dans ELISA. Il présente une réactivité envers Souris.

Aperçu rapide pour Caspase 1 anticorps (ABIN1305223)

Antigène: Caspase 1 (CASP1)

Reactivité: Souris

Hôte: Veuillez nous consulter SVP

Conjugué: Cet anticorp Caspase 1 est non-conjugé

Application: ELISA

Détail du produit anti-Caspase 1 anticorps

Gamme de detection: 0.15ng/mL – 10ng/mL

Seuil minimal de détection: 100pg/ml

Specificité: Detects mouse Caspase-1 (p10 and p20 domain). Does not detect human Caspase-1.

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Stock: -20 °C

Détails sur Caspase 1

Antigène: Caspase 1 (CASP1)

Autre désignation: Caspase-1

Sujet: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals._x000D_The Caspase-1 (mouse) Matched Pair Detection Set contains all reagents for the development of a sandwich ELISA to measure Caspase-1 (mouse) in cell culture supernatants. This Matched Pair Detection Set is a quantitative alternative to Western blotting to measure inflammasome activation leading to Caspase-1 cleavage and secretion.

Pathways: Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome