Caspase 1 anticorps

N° du produit ABIN1305223

Détail du produit anti-Caspase 1 anticorps

Antigène: Caspase 1 (CASP1)

Reactivité: Souris

Hôte: Veuillez nous consulter SVP

Conjugué: Cet anticorp Caspase 1 est non-conjugé

Gamme de detection: 0.15ng/mL – 10ng/mL

Seuil minimal de détection: 100pg/ml

Application: ELISA

Specificité: Detects mouse Caspase-1 (p10 and p20 domain). Does not detect human Caspase-1.

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Stock: -20 °C

Détails sur Caspase 1

Antigène: Caspase 1 (CASP1)

Autre désignation: Caspase-1 (CASP1 Produits)

Synonymes: anticorps ICE, anticorps IL1BC, anticorps P45, anticorps Il1bc, anticorps Ice, anticorps CASP1, anticorps CG5370, anticorps DCP-1, anticorps DCP1, anticorps Dcp1, anticorps Dmel\\CG5370, anticorps ccp1, anticorps dcp-1, anticorps dcp1, anticorps l(2)01862, anticorps l(2)02132, anticorps caspase 1, anticorps caspase 1, apoptosis-related cysteine peptidase, anticorps caspase 4, apoptosis-related cysteine peptidase, anticorps Death caspase-1, anticorps caspase-1, anticorps caspase, anticorps caspase recruitment domain-containing protein 16, anticorps caspase 4, anticorps CASP1, anticorps Casp1, anticorps CASP4, anticorps Dcp-1, anticorps Caspase1, anticorps LOC5564196, anticorps LOC451519

Sujet: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals._x000D_The Caspase-1 (mouse) Matched Pair Detection Set contains all reagents for the development of a sandwich ELISA to measure Caspase-1 (mouse) in cell culture supernatants. This Matched Pair Detection Set is a quantitative alternative to Western blotting to measure inflammasome activation leading to Caspase-1 cleavage and secretion.

Pathways: Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome