CD44 anticorps

N° du produit ABIN135069

Cet anticorps anti-CD44 Monoclonal Rat (Clone KM201) (ABIN135069) détecte spécifiquement CD44 dans FACS, WB, IHC (p), IP, IHC (fro), ICC, BR et Adh Act. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour CD44 anticorps (ABIN135069)

Antigène: CD44

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Blocking Reagent (BR), Adhesion Activation (Adh Act)

Clone: KM201

Détail du produit anti-CD44 anticorps

Fonction: Rat Anti-Mouse CD44-LE/AF

Specificité: Mouse CD44 (all isoforms), Mr 80-95 kDa

Attributs du produit: Low Endotoxin/Azide Free Anti-Mouse CD44 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, blocking, and adhesion assays.

niveau d'endotoxine: Low Endotoxin

Immunogène: (C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal clone BMS2

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: 2-8°C

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte Cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.

ID gène: 12505

UniProt: P15379

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling