CD19 anticorps

N° du produit ABIN135152

L’anticorps anti-CD19 Monoclonal Rat est utilisé pour la détection de CD19 dans des échantillons de Souris. Il a été validé pour FACS, IP, IHC (fro) et Sep.

Aperçu rapide pour CD19 anticorps (ABIN135152)

Antigène: CD19 (CD19 Molecule (CD19))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD19 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Separation (Sep)

Clone: 6D5

Détail du produit anti-CD19 anticorps

Fonction: Rat Anti-Mouse CD19-LE/AF

Specificité: Mouse CD19, Mr 95 kDa

Attributs du produit: Low Endotoxin/Azide Free Anti-Mouse CD19 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, and separation assays.

niveau d'endotoxine: Low Endotoxin

Immunogène: Mouse CD19-expressing K562 human erythroleukemia cells

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: 2-8°C

Détails sur CD19

Antigène: CD19 (CD19 Molecule (CD19))

Autre désignation: CD19

Sujet: CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Recent studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow.

ID gène: 12478

UniProt: P25918

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway