CD25 anticorps

N° du produit ABIN135175

Cet anticorps Rat Monoclonal détecte spécifiquement CD25 dans FACS, IP, IHC (fro), BR, Neut, Dep et CMCD. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour CD25 anticorps (ABIN135175)

Antigène: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD25 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Neutralization (Neut), Depletion (Dep), Complement Mediated Cell Depletion (CMCD)

Clone: 7D4

Détail du produit anti-CD25 anticorps

Fonction: Rat Anti-Mouse CD25-LE/AF

Specificité: Mouse CD25, Mr 55 kDa

Attributs du produit: Low Endotoxin/Azide Free Anti-Mouse CD25 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, blocking, depletion, CMCD, and neutralization assays.

niveau d'endotoxine: Low Endotoxin

Immunogène: IL-2 dependent BALB/c helper T cell clone HT2

Isotype: IgM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: 2-8°C

Détails sur CD25

Antigène: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Autre désignation: CD25

Sujet: The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells and monocytes of all mouse strains tested. It is transiently expressed at a low level during B-cell development in bone marrow on the CD45R/B220low TdT- sIg- pre-B II and CD45R/B220low TdT- sIgM+sIgD- immature B cells, but not on the CD45R/B220low TdT+ sIg- pro-B/pre-B I stage nor on CD45R/B220high TdT- sIgM+sIgD+ mature B cells. CD25 is expressed at a higher level during very early T-cell development in fetal and adult thymus.

ID gène: 16184

UniProt: P01590

Pathways: Signalistation JAK/STAT, Growth Factor Binding, Activated T Cell Proliferation