Transferrin Receptor anticorps

N° du produit ABIN135263

L’anticorps anti-Transferrin Receptor Monoclonal Rat est utilisé pour la détection de Transferrin Receptor dans des échantillons de Souris. Il a été validé pour FACS, WB, IP, ICC, BR, DD et Sep.

Aperçu rapide pour Transferrin Receptor anticorps (ABIN135263)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Blocking Reagent (BR), Drug Delivery (DD), Separation (Sep)

Clone: RI7217

Détail du produit anti-Transferrin Receptor anticorps

Fonction: Rat Anti-Mouse CD71-LE/AF

Specificité: Mouse CD71, Mr 95 kDa

Attributs du produit: Low Endotoxin/Azide Free Anti-Mouse CD71 antibody for use in flow cytometry, immunocytochemistry, western blotting, immunoprecipitation, blocking, separation, and drug delivery assays.

niveau d'endotoxine: Low Endotoxin

Immunogène: DMSO induced Friend erythroleukemia 745.6

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: 2-8°C

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: CD71

Sujet: CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens, presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor chain.

ID gène: 22042

UniProt: Q62351

Pathways: Transition Metal Ion Homeostasis