CD80 anticorps (PE)

N° du produit ABIN135271

Cet anticorps Rat Monoclonal détecte spécifiquement CD80 dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour CD80 anticorps (PE) (ABIN135271)

Antigène: CD80

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD80 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: 1G10

Détail du produit anti-CD80 anticorps (PE)

Specificité: Mouse CD80, Mr 52-55 kDa

Attributs du produit: Rat Anti-Mouse CD80-PE

Purification: Ion exchange column

Immunogène: Activated 5C2 cells

Isotype: IgG2a

Information d'application

Indications d'application:

• Applications: FC - Quality tested , IP - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Commentaires:

In vivo and in vitro blocking of ligand binding

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/Sodium azide and a stabilizing agent

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Détails sur CD80

Antigène: CD80

Autre désignation: CD80

Sujet: CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex.

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints