CD80 anticorps
Aperçu rapide pour CD80 anticorps (ABIN135272)
Antigène
Voir toutes CD80 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Rat Anti-Mouse CD80-LE/AF
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Specificité
- Mouse CD80, Mr 52-55 kDa
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Attributs du produit
- Low Endotoxin/Azide Free Anti-Mouse CD80 antibody for use in flow cytometry, immunoprecipitation, and blocking assays.
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niveau d'endotoxine
- Low Endotoxin
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Immunogène
- Activated 5C2 cells
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate buffered saline, pH 7.4
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Agent conservateur
- Azide free
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Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C
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- CD80
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Autre désignation
- CD80
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Sujet
- CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex.
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ID gène
- 12519
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UniProt
- Q00609
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Antigène
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