Cytochrome C anticorps (AA 71-75)

N° du produit ABIN1355829

Cet anticorps anti-Cytochrome C Polyclonal Lapin (ABIN1355829) détecte spécifiquement Cytochrome C dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Cytochrome C anticorps (AA 71-75) (ABIN1355829)

Antigène: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cytochrome C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cytochrome C anticorps

Épitope: AA 71-75

Specificité: The antibody detects endogenous level of total Cytochrome C protein.

Immunogène: Peptide sequence around AA 71-75 (N-P-K-K-Y) derived from Human Cytochrome C.

Information d'application

Indications d'application: Western blotting: 1: 500-1: 1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C/-20 °C

Détails sur Cytochrome C

Antigène: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Autre désignation: Cytochrome C

Sujet: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

Poids moléculaire: 14 kDa

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity