CD14 anticorps

N° du produit ABIN135743

L’anticorps anti-CD14 Monoclonal produit chez le Souris a été validé pour FACS. Il convient pour la détection de CD14 dans des échantillons provenant de Humain. }

Aperçu rapide pour CD14 anticorps (ABIN135743)

Antigène: CD14

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: UCHM-1

Détail du produit anti-CD14 anticorps

Specificité: Human/Cynomolgus CD14, Mr 55 kDa

Attributs du produit: Mouse Anti-Human CD14-UNLB

Purification: Purified

Immunogène: Thymocytes and peripheral blood lymphocytes from a remission AML patient

Isotype: IgG2a

Information d'application

Indications d'application:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , ELISA - Reported in literature , Block - Reported in literature , Depletion - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, and SPRD conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Agent conservateur: Without preservative

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: CD14 is a 53-55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades