FAS anticorps

N° du produit ABIN135817

Cet anticorps Souris Monoclonal détecte spécifiquement FAS dans FACS, ELISA, IP, ICC, IHC (fro), IHC (p) et AD. Il présente une réactivité avec des échantillons de Humain, Macaque rhésus, Sooty mangabey (Cercocebus atys) et Green Monkey.

Aperçu rapide pour FAS anticorps (ABIN135817)

Antigène: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reactivité: Humain, Macaque rhésus, Sooty mangabey (Cercocebus atys), Green Monkey

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FAS est non-conjugé

Application: Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Apoptosis Detection (AD)

Clone: DX2

Détail du produit anti-FAS anticorps

Fonction: Mouse Anti-Human CD95-LE/AF

Specificité: Human/Rhesus/African Green Monkey/Sooty Mangabey CD95, Mr 45 kDa

Attributs du produit: Low Endotoxin/Azide Free Anti-Human CD95 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, ELISA, and apoptosis assays.

niveau d'endotoxine: Low Endotoxin

Immunogène: Human CD95 transfected L cells

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: 2-8°C

Détails sur FAS

Antigène: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Autre désignation: CD95

Sujet: CD95, also known as Fas and Apo-1, is a 40-50 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance. Crosslinking of CD95 by the monoclonal antibodies DX2 and DX3 delivers an apoptotic signal to Fas-sensitive cells, indicating that these monoclonal antibodies recognize a functional epitope of CD95.

ID gène: 355, 574332, 103216224

UniProt: P25445

Pathways: Signalisation p53, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity