IL-6 Receptor anticorps

N° du produit ABIN1383676

Cet anticorps Souris Monoclonal détecte spécifiquement IL-6 Receptor dans ELISA et FACS. Il présente une réactivité envers Humain et a été mentionné dans 5+ publications.

Aperçu rapide pour IL-6 Receptor anticorps (ABIN1383676)

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-6 Receptor est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: B-N12

Détail du produit anti-IL-6 Receptor anticorps

Specificité: Recognises the Interleukin-6 Ra subunit, IL-6 Ra, IL-6 R, a 80 kDa protein

Purification: Ion exchange chromatography

Stérilité: 0.22 μm filtered

Immunogène: gp80 transfected CHO cell line,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Agent conservateur: Without preservative

Stock: 4 °C

Stockage commentaire: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

Références pour anticorps anti-IL-6 Receptor (ABIN1383676)

Labbozzetta, Notarbartolo, Poma, Giannitrapani, Cervello, Montalto, DAlessandro: "Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma." dans: Annals of the New York Academy of Sciences, Vol. 1089, pp. 268-75, (2007) (PubMed).

Kube, Holtick, Vockerodt, Ahmadi, Haier, Behrmann, Heinrich, Diehl, Tesch: "STAT3 is constitutively activated in Hodgkin cell lines." dans: Blood, Vol. 98, Issue 3, pp. 762-70, (2001) (PubMed).

Lebeau, Montero Julian, Wijdenes, Müller-Newen, Dahmen, Chérel, Heinrich, Brailly, Hallet, Godard, Minvielle, Jacques: "Reconstitution of two isoforms of the human interleukin-11 receptor and comparison of their functional properties." dans: FEBS letters, Vol. 407, Issue 2, pp. 141-7, (1997) (PubMed).

Müller-Newen, Köhne, Keul, Hemmann, Müller-Esterl, Wijdenes, Brakenhoff, Hart, Heinrich: "Purification and characterization of the soluble interleukin-6 receptor from human plasma and identification of an isoform generated through alternative splicing." dans: European journal of biochemistry / FEBS, Vol. 236, Issue 3, pp. 837-42, (1996) (PubMed).

Mouthon, Freund, Titeux, Katz, Guichard, Breton-Gorius, Vainchenker: "Growth and differentiation of the human megakaryoblastic cell line (ELF-153): a model for early stages of megakaryocytopoiesis." dans: Blood, Vol. 84, Issue 4, pp. 1085-97, (1994) (PubMed).

Détails sur IL-6 Receptor

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Autre désignation: CD126

Sujet: IL-6R / gp80

Poids moléculaire: 80 kDa

Pathways: Signalistation JAK/STAT, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints