Metabotropic Glutamate Receptor 3 anticorps (AA 365-460)

N° du produit ABIN1386656

Détail du produit anti-Metabotropic Glutamate Receptor 3 anticorps

Antigène: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Épitope: AA 365-460

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 3 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Metabotropic Glutamate Receptor 3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Metabotropic Glutamate Receptor 3

Antigène: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Autre désignation: MGLUR3 (GRM3 Produits)

Synonymes: anticorps GLUR3, anticorps GPRC1C, anticorps MGLUR3, anticorps mGlu3, anticorps 0710001G23Rik, anticorps Gprc1c, anticorps mGluR3, anticorps glutamate metabotropic receptor 3, anticorps glutamate receptor, metabotropic 3, anticorps GRM3, anticorps Grm3

Sujet:

Synonyms: G protein coupled receptor family C group 1 member C, GLUR 3, GLUR3, GLUR3, Glutamate metabotropic receptor 3, Glutamate receptor metabotropic 3, GPRC1C, GRM 3, GRM3, GRM3_HUMAN, Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 3 precursor, mGlu 3, MGlu3, MGlu3, MGLUR 3, MGLUR3.

Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.

Pathways: cAMP Metabolic Process, Synaptic Membrane