PRMT5 anticorps (AA 201-300)
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- Antigène Voir toutes PRMT5 Anticorps
- PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))
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Épitope
- AA 201-300
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PRMT5 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Dog,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human PRMT5
- Isotype
- IgG
- Top Product
- Discover our top product PRMT5 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))
- Autre désignation
- PRMT5 (PRMT5 Produits)
- Synonymes
- anticorps HRMT1L5, anticorps IBP72, anticorps JBP1, anticorps SKB1, anticorps SKB1Hs, anticorps Jbp1, anticorps Skb1, anticorps si:zc14a17.2, anticorps skb1, anticorps wu:fb95f10, anticorps zgc:110669, anticorps hsl7, anticorps DDBDRAFT_0187422, anticorps DDBDRAFT_0235403, anticorps DDB_0187422, anticorps DDB_0235403, anticorps NV18830, anticorps jbp1, anticorps ibp72, anticorps skb1hs, anticorps hrmt1l5, anticorps protein arginine methyltransferase 5, anticorps protein arginine N-methyltransferase 5, anticorps protein arginine methyltransferase 5 L homeolog, anticorps putative arginine N-methyltransferase, type II, anticorps Skb1 family protein, anticorps Protein arginine N-methyltransferase 5, anticorps PRMT5, anticorps Prmt5, anticorps prmt5, anticorps prmt5.L, anticorps LOC100115766, anticorps prmt-5
- Sujet
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Synonyms: 72 kDa ICln binding protein, 72 kDa ICln-binding protein, ANM5_HUMAN, Histone-arginine N-methyltransferase PRMT5, HMT1 hnRNP methyltransferase like 5, HOMOLOG OF, SKB1, HRMT1L5, IBP72, Jak-binding protein 1, JBP 1, JBP1, PRMT 5, PRMT5, Protein arginine methyltransferase 5, Protein arginine N methyltransferase 5, Protein arginine N-methyltransferase 5, S. POMBE, S. POMBE HOMOLOG OF, SKB1, SHK1 KINASE BINDING PROTEIN 1, Shk1 kinase binding protein 1 homolog, SHK1 KINASE-BINDING PROTEIN 1, Shk1 kinase-binding protein 1 homolog, SKB 1, SKB1, SKB1 homolog, SKB1: SKB1 homolog S. pombe, SKB1Hs.
Background: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10.
- ID gène
- 10419
- Pathways
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
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