TFAM anticorps (AA 155-246)

N° du produit ABIN1387734

Cet anticorps anti-TFAM est un anticorps Lapin Polyclonal détectant TFAM dans WB, ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Adapté pour Souris et Rat. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour TFAM anticorps (AA 155-246) (ABIN1387734)

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFAM est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TFAM anticorps

Épitope: AA 155-246

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig,Rabbit,Goat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MtTF1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-TFAM (ABIN1387734)

Yan, Liu, Guan, Guo: "Deferoxamine ameliorates adipocyte dysfunction by modulating iron metabolism in ob/ob mice." dans: Endocrine connections, Vol. 7, Issue 4, pp. 604-616, (2018) (PubMed).

You, Hou, Zhai, Li, Li, Zhao, Zhao: "Protective effects of PGC-1α via the mitochondrial pathway in rat brains after intracerebral hemorrhage." dans: Brain research, Vol. 1646, pp. 34-43, (2016) (PubMed).

Yan, Ji, Shi, Li, Sang: "Acute nitrogen dioxide inhalation induces mitochondrial dysfunction in rat brain." dans: Environmental research, Vol. 138, pp. 416-24, (2015) (PubMed).

Détails sur TFAM

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Autre désignation: MtTF1

Sujet:

Synonyms: TCF6, MTTF1, MTTFA, TCF6L1, TCF6L2, TCF6L3, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, TCF-6, Transcription factor 6-like 2, TFAM

Background: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.

ID gène: 7019

UniProt: Q00059

Pathways: Chromatin Binding