HNF4A anticorps (pSer303)

N° du produit ABIN1387865

L’anticorps Lapin Polyclonal anti-HNF4A a été validé pour WB, ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Il convient pour détecter HNF4A dans des échantillons de Souris et Poisson zèbre (Danio rerio).

Aperçu rapide pour HNF4A anticorps (pSer303) (ABIN1387865)

Antigène: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Reactivité: Souris, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNF4A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-HNF4A anticorps

Épitope: pSer303

Réactivité croisée: Souris, Poisson zèbre (Danio rerio)

Homologie: Human,Rat,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human HNF4 alpha around the phosphorylation site of Ser303

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur HNF4A

Antigène: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Autre désignation: HNF4

Sujet:

Synonyms: HNF4Ser303, Hepatic nuclear factor 4 alpha, Hepatocyte nuclear factor 4 alpha, Hepatocyte nuclear factor 4, HNF 4 alpha, HNF 4, HNF4, HNF4A, HNF4a7, HNF4a8, HNF4a9, Hnf4alpha, MODY 1, MODY, MODY1, NR2A1, NR2A21, Nuclear receptor subfamily 2 group A member 1, TCF 14, TCF, TCF14, Tcf4, Transcription factor 14, hepatic nuclear factor, Transcription factor 14, Transcription factor HNF 4, Transcription factor HNF4, HNF4A_HUMAN.

Background: The protein encoded by the HNF4 gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin dependent diabetes mellitus type I. At least three different transcript variants encoding three different isoforms have been found for this gene.

ID gène: 3172

Pathways: AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process