Complement C4 anticorps (AA 701-800) (Biotin)

N° du produit ABIN1390297

Cet anticorps Lapin Polyclonal détecte spécifiquement Complement C4 dans ELISA, IHC (fro) et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Complement C4 anticorps (AA 701-800) (Biotin) (ABIN1390297)

Antigène: Complement C4 (C4) (Complement 4 (C4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Complement C4 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Complement C4 anticorps (Biotin)

Épitope: AA 701-800

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Complement C4 C4a anaphylatoxin or complement C4 alpha chain

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Complement C4

Antigène: Complement C4 (C4) (Complement 4 (C4))

Autre désignation: Complement C4/C4

Sujet:

Synonyms: C4a anaphylatoxin, Complement C4-A alpha chain, complement C4-A proprotein, Acidic C4, Acidic complement C4, Basic C4, Basic complement C4, C4 Anaphylatoxin, C4 complement C4d region, complement C4 alpha chain, C4A, C4A13, C4A2, C4A3, C4A4, C4A6, C4A91, C4B, C4B1, C4B12, C4B2, C4B3, C4B5, C4F, C4S, CH, Chido form of C4, CO4, Complement C4 A, Complement C4 B, Complement C4B, Complement component 4A Rodgers blood group, Complement component 4A, Complement component 4B Childo blood group, Complement component 4B, Complement component C4B, CPAMD2, CPAMD3. RG, Rodgers Form Of C4.

Background: This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

ID gène: 720, 721

Pathways: Système du Complément