NLRX1 anticorps (AA 111-210) (AbBy Fluor® 555)

N° du produit ABIN1399469

L’anticorps Lapin Polyclonal anti-NLRX1 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter NLRX1 dans des échantillons de Humain.

Aperçu rapide pour NLRX1 anticorps (AA 111-210) (AbBy Fluor® 555) (ABIN1399469)

Antigène: NLRX1 (NLR Family Member X1 (NLRX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRX1 est conjugé à/à la AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-NLRX1 anticorps (AbBy Fluor® 555)

Épitope: AA 111-210

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NLR family member X1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur NLRX1

Antigène: NLRX1 (NLR Family Member X1 (NLRX1))

Autre désignation: NLRX1

Sujet:

Synonyms: NOD5, NOD9, NOD26, DLNB26, CLR11.3, NLR family member X1, Caterpiller protein 11.3, Nucleotide-binding oligomerization domain protein 26, Nucleotide-binding oligomerization domain protein 5, Nucleotide-binding oligomerization domain protein 9, NLRX1

Background: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).

ID gène: 79671

UniProt: Q86UT6

Pathways: SARS-CoV-2 Protein Interactome