Dihydrofolate Reductase anticorps (AbBy Fluor® 350)
Aperçu rapide pour Dihydrofolate Reductase anticorps (AbBy Fluor® 350) (ABIN1400589)
Antigène
Voir toutes Dihydrofolate Reductase (DHFR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- DHFR Polyclonal Antibody, AbBy Fluor-350 Conjugated
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Réactivité croisée
- Humain, Souris
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human DHFR
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Isotype
- IgG
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anti-Dihydrofolate Reductase (DHFR) (AA 88-187) antibody
DHFR Reactivité: Humain WB, ELISA, IF Hôte: Souris Monoclonal 2B10 unconjugated
anti-Dihydrofolate Reductase (DHFR) antibodyDHFR Reactivité: Humain, Chien, Singe WB, IHC, IF, IHC (p) Hôte: Souris Monoclonal 6G7 unconjugated
anti-Dihydrofolate Reductase (DHFR) (AA 2-187) antibodyDHFR Reactivité: Humain, Souris, Rat WB, IHC, IF, FACS, ICC Hôte: Lapin Polyclonal unconjugated
anti-Dihydrofolate Reductase (DHFR) antibodyDHFR Reactivité: Humain WB, IHC, ELISA, IP Hôte: Lapin Monoclonal 9B2 unconjugated Recombinant Antibody
anti-Dihydrofolate Reductase (DHFR) antibodyKD Validated DHFR Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB3575 unconjugated Recombinant Antibody
anti-Dihydrofolate Reductase (DHFR) (AA 1-50) antibodyDHFR Reactivité: Humain, Souris, Rat WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Dihydrofolate Reductase (DHFR) (AA 135-164) antibodyDHFR Reactivité: Souris WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Dihydrofolate Reductase (DHFR) (AA 16-30), (N-Term) antibodyDHFR Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal RB49346 unconjugated
anti-Dihydrofolate Reductase (DHFR) (AA 1-187) antibodyDHFR Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Dihydrofolate Reductase (DHFR) (AA 1-186) antibodyDHFR Reactivité: Humain, Souris, Rat, Chien WB, IHC, IF, IP Hôte: Souris Monoclonal 49-DHFR unconjugated
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Indications d'application
- IF(1:50-200)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- Dihydrofolate Reductase (DHFR)
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Autre désignation
- DHFR
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Sujet
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Synonyms: DHFR, DHFRP1, Dihydrofolate reductase, DYR, DYR_HUMAN, EC 1.5.1.3.
Background: DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and is a crucial enzyme for the synthesis of purines, pyrimidines and some amino acids. Inhibition of the activity of this enzyme leads to arrest of DNA synthesis and cell death. Gene expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive.
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Poids moléculaire
- 21kDa
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ID gène
- 1719
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HGNC
- 0
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UniProt
- P00374
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Pathways
- Mitotic G1-G1/S Phases
Antigène
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