Dihydrofolate Reductase anticorps (AA 88-187)

N° du produit ABIN560600

Il existe 6+ publications pour ce produit. L’anticorps anti-Dihydrofolate Reductase Monoclonal Souris est utilisé pour la détection de Dihydrofolate Reductase dans des échantillons de Humain. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour Dihydrofolate Reductase anticorps (AA 88-187) (ABIN560600)

Antigène: Dihydrofolate Reductase (DHFR)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Dihydrofolate Reductase est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 2B10

Détail du produit anti-Dihydrofolate Reductase anticorps

Épitope: AA 88-187

Fonction: Mouse monoclonal antibody raised against a partial recombinant DHFR.

Séquence: HFLSRSLDDA LKLTEQPELA NKVDMVWIVG GSSVYKEAMN HPGHLKLFVT RIMQDFESDT FFPEIDLEKY KLLPEYPGVL SDVQEEKGIK YKFEVYEKND

Réactivité croisée: Humain, Rat

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: DHFR (AAH03584, 88 a.a. ~ 187 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-Dihydrofolate Reductase (ABIN560600)

Jabs, Oelze, Mikhed, Stamm, Kröller-Schön, Welschof, Jansen, Hausding, Kopp, Steven, Schulz, Stasch, Münzel, Daiber: "Effect of soluble guanylyl cyclase activator and stimulator therapy on nitroglycerin-induced nitrate tolerance in rats." dans: Vascular pharmacology, Vol. 71, pp. 181-91, (2015) (PubMed).

Kossmann, Hu, Steven, Schönfelder, Fraccarollo, Mikhed, Brähler, Knorr, Brandt, Karbach, Becker, Oelze, Bauersachs, Widder, Münzel, Daiber, Wenzel: "Inflammatory monocytes determine endothelial nitric-oxide synthase uncoupling and nitro-oxidative stress induced by angiotensin II." dans: The Journal of biological chemistry, Vol. 289, Issue 40, pp. 27540-50, (2014) (PubMed).

Oelze, Kröller-Schön, Welschof, Jansen, Hausding, Mikhed, Stamm, Mader, Zinßius, Agdauletova, Gottschlich, Steven, Schulz, Bottari, Mayoux, Münzel, Daiber et al.: "The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozotocin diabetes rat model by interfering with oxidative stress and ..." dans: PLoS ONE, Vol. 9, Issue 11, pp. e112394, (2014) (PubMed).

Vodenicharov, Laterreur, Wellinger: "Telomere capping in non-dividing yeast cells requires Yku and Rap1." dans: The EMBO journal, Vol. 29, Issue 17, pp. 3007-19, (2010) (PubMed).

Yoon, Choi, Kim, Shin, Zhang, Kang: "Influence of reduced folate carrier and dihydrofolate reductase genes on methotrexate-induced cytotoxicity." dans: Cancer research and treatment : official journal of Korean Cancer Association, Vol. 42, Issue 3, pp. 163-71, (2010) (PubMed).

Ionova, Vásquez-Vivar, Whitsett, Herrnreiter, Medhora, Cooley, Pieper: "Deficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytes." dans: American journal of physiology. Heart and circulatory physiology, Vol. 295, Issue 5, pp. H2178-87, (2008) (PubMed).

Détails sur Dihydrofolate Reductase

Antigène: Dihydrofolate Reductase (DHFR)

Autre désignation: DHFR

Sujet: Full Gene Name: dihydrofolate reductase
Synonyms:

ID gène: 1719

Pathways: Mitotic G1-G1/S Phases