Dihydrofolate Reductase anticorps (AA 1-187)

N° du produit ABIN3022228

Détail du produit anti-Dihydrofolate Reductase anticorps

Antigène: Dihydrofolate Reductase (DHFR)

Épitope: AA 1-187

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dihydrofolate Reductase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MVGSLNCIVA VSQNMGIGKN GDLPWPPLRN EFRYFQRMTT TSSVEGKQNL VIMGKKTWFS IPEKNRPLKG RINLVLSREL KEPPQGAHFL SRSLDDALKL TEQPELANKV DMVWIVGGSS VYKEAMNHPG HLKLFVTRIM QDFESDTFFP EIDLEKYKLL PEYPGVLSDV QEEKGIKYKF EVYEKND

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human DHFR (NP_000782.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Dihydrofolate Reductase

Antigène: Dihydrofolate Reductase (DHFR)

Autre désignation: DHFR (DHFR Produits)

Synonymes: anticorps DHFR, anticorps F10_orf160, anticorps ECK0049, anticorps JW0047, anticorps tmrA, anticorps cb595, anticorps zgc:86637, anticorps DDBDRAFT_0187132, anticorps DDBDRAFT_0230113, anticorps DDB_0187132, anticorps DDB_0230113, anticorps CG14887, anticorps Dmel\\CG14887, anticorps dhfr, anticorps DHFRP1, anticorps DYR, anticorps 8430436I03Rik, anticorps AA607882, anticorps AI662710, anticorps AW555094, anticorps Dhfr1, anticorps confers resistance to sulfonamides, anticorps dihydrofolate reductase, anticorps dihydrofolate reductase DhfR, anticorps Dihydrofolate reductase, anticorps dhfr, anticorps DHFR, anticorps dhfR, anticorps folA, anticorps dfrA, anticorps LOC707382, anticorps CNJ01940, anticorps DDB_G0286755, anticorps Dhfr, anticorps Mesil_0096, anticorps Arch_0408, anticorps Fbal_3367, anticorps Ilyop_0482, anticorps Lbys_2007, anticorps Riean_0733, anticorps Mrub_1855, anticorps Poras_0766, anticorps Halhy_3552, anticorps Mesop_3614, anticorps LOC609048

Sujet: Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene.,DHFR,DHFRP1,DYR,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,Nucleotide metabolism,DHFR

Poids moléculaire: 15 kDa/21 kDa

ID gène: 1719

UniProt: P00374

Pathways: Mitotic G1-G1/S Phases