SNIP1 anticorps (AA 301-396) (HRP)

N° du produit ABIN1408112

L’anticorps Lapin Polyclonal anti-SNIP1 a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter SNIP1 dans des échantillons de Humain.

Aperçu rapide pour SNIP1 anticorps (AA 301-396) (HRP) (ABIN1408112)

Antigène: SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNIP1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-SNIP1 anticorps (HRP)

Épitope: AA 301-396

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SNIP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SNIP1

Antigène: SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))

Autre désignation: SNIP1

Sujet:

Synonyms: FHA domain-containing protein SNIP1, FLJ12553, Smad nuclear interacting protein Smad nuclear interacting, Smad nuclear interacting protein, Smad nuclear-interacting protein 1, SNIP1 Smad nuclear interacting protein, SNIP1, SNIP1_HUMAN, Splicing factor arginine/serine rich 4 Pre mRNA splicing factor SRP75.

Background: Members of the transforming growth factor-beta (TGF-Beta) superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-Beta family ligands are mediated by Smad proteins. The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. SNIP1 potently inhibits the activity of NF-kappa B, which binds the C/H1 domain of CBP/p300, by competing for the binding site. SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation. SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle.

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2